Post-Docs
| Name | Year(s) | Project | Where Are They Now? |
|---|---|---|---|
| Christine Wurth | 2000 – 2002 | Mapping the Sequence Determinants of the Aggregation of the Alzheimer’s A-beta Peptide | Hoffmann-La Roche Ltd, Basel, Switzerland |
| Luke Bradley | 2001 – 2006 | Design and Construction of Combinatorial Libraries of Novel Proteins | Assistant Professor, University of Kentucky Medical School, Lexington, KY. |
| Michael Ackerman | 2003 – 2005 | Structural Studies of de Novo Designed Beta Sheet Proteins | Bristol-Myers Squibb, Princeton NJ. |
| Ryoichi Arai | 2006 – 2007 | Phage Display of Combinatorial Libraries of Novel Proteins | Assistant Professor, Shinshu University, Nagano, Japan. |
| Izhack Cherny | 2007 – 2011 | Functional Proteins from an Artificial Proteome | Felsenstein Medical Research Center |
| Betsy Smith | 2010 – 2014 | Laboratory evolution of de novo proteins toward higher activity and enhanced specificity | Assistant Professor, Elimra College |
| Grant S. Murphy | 2012-2016 | Computational/Combinatorial Design of Libraries of Stable Proteins | Merck Inc. |
Graduate Students
| Name | Department | Year(s) | Thesis Title | Where Are They Now? |
|---|---|---|---|---|
| Dave Moffet | Chemistry | Ph.D. 2002 | Functional Proteins From a Designed Combinatorial Library | Associate Professor, Loyola Marymount University, Los Angeles, CA. |
| Yinan Wei | Chemistry | Ph.D. 2003 | Structural and Functional Studies of Well Folded Alpha Helical Proteins from a Designed Combinatorial Library | Associate Professor, University of Kentucky, Lexington, KY. |
| Aditi Das | Chemistry | Ph.D. 2005 | Electrochemical and Functional Studies of de Novo Alpha Helical Proteins from a Designed Combinatorial Library | Assistant Professor, University of Illinois-Urbana Champaign |
| Woojin Kim | Chemistry | Ph.D. 2006 | Sequence Determinants and Inhibition of the Aggregation of the Alzheimer’s ABeta Peptide | Harvard Medical School |
| Abi Go | Chemistry | Ph.D. 2008 | Structural and Dynamics of de Novo Proteins form a Designed Superfamily of 4-Helix Bundles | Univeristy of Houston Law School |
| Shona Patel | Chemical Engineering | Ph.D. 2008 | The Functional Potential of De Novo Designed Four-Helix Bundle Proteins | Merck Inc, West Point, PA. |
| Jermont Chen | Chemistry | Ph.D. 2008 | Using High Throughput Screens to Identify Lead Compounds for Alzheimer’s Disease Theraputics | Propulsion Directorate, Wright-Patterson Air Force Base, OH. |
| Mike Fisher | Molecular Biology | Ph.D. 2009 | Toward de Novo Genomes Informed by Protein Design | University of California – Berkley. |
| Emily Breneman | Chemistry | M.A. | Screening de Novo Four-Helix Bundle Protein Libraries for Enzymatic Activity Using mRNA Display | Vector Biolabs, Inc., Recording for the Blind & Dyslexic |
| Angela Fortner-McKoy | Chemistry | Ph.D 2011 | Characterization of Novel Inhibitors of Alzheimer’s Peptide Aggregation and Implications for Disease Therapeutics | Lecturer, Wheaton College |
| Maria Korolev | Chemistry | Ph.D 2013 | Investigating the mechanism of two synthetic proteins found to rescue E. coli auxotrophic strains ΔgltA and Δges | Lecturer at University of Florida |
| Ann Donnelly | Chemistry | Ph.D 2016 | Exploring the Functional Potential of de novo Proteins | University of Pittsburg |
| Katie Digianantonio | Chemistry | Ph.D 2016 | Uncovering the Mechanism by which de novo Designed Proteins Rescue Auxotrophic E. coli cells | Post-Doc, Yale University |
| Kenric Hoegler | Molecular Biology | Ph.D 2016 | Natural and de novo Proteins in Transition Metal Binding and Toxicity | Senior Analyst, Insight Strategy Advisors, |
Undergraduate Students
| Name | Department | Year(s) | Thesis Title | Where Are They Now? |
|---|---|---|---|---|
| Anna Wang | Chemistry | AB 2006 | Sequence, Expression, and Structural Characterization of a High-Quality De Novo Combinatorial Four Helix Bundle Library | Harvard University, Cambridge MA |
| Jesse Platt | Chemistry | AB 2007 | Biophysical Characterization of De Novo Four Helix Bundle Proteins | University of Pennsylvania Medical School, Philidelphia PA. |
| Ellen Duncan | Chemistry | AB 2007 | Expression and Enzymatic Activity in Proteins from a Combinatorial Library of De Novo Proteins | Columbia University Medical School |
| Debbie Chen | Molecular Biology | AB 2007 | The Aβ42-GFP Fusion Screen: A High Throughput Screen for Compounds that Inhibit Aggregation of the Alzheimer’s Peptide | University of Connecticut Medical School |
| Sayuri Jinadasa | Chemistry | AB 2008 | Screening, Purification, and Kinetic Characterization of de novo Proteins from a Designed Combinatorial Library | Columbia University Medical School, New York, NY. |
| Anne Armstrong | Chemistry | AB 2008 | Exploring the Primary Sequence Det, erminants of Amyloid Beta Aggregation: Towards a Targeted Therapeutic Approach to Alzheimer’s Disease | Mount Sinai Medical School |
| Sara Viola | Molecular Biology | AB 2008 | Novel Proteins from a Designed Combinatorial Library Restore Prototrophy in Single Gene knockouts of Escherichia Coli. | Columbia University Medical School, New York, NY |
| Steve Sasson | Chemistry | AB 2009 | A Bacterial Surface Display Library for the High-Throughput Screening and Selection of De Novo Designed Four-Helix Bundle Proteins | JP Morgan, New York, NY |
| Sam Leachman | Chemistry | AB 2009 | Redesigning a Dynamic Artificial Protein | University of California, Berkeley |
| Beverly Hon | Molecular Biology | AB 2009 | Novel Proteins from a Designed Combinatorial Library Suppress Conditional Auxotrophs in Saccharomyces Cerevisiae | University of Medicine and Dentistry of New Jersey |
| Jessica Langholtz | Chemistry | AB 2009 | Screening and Enzymatic Characterization of De Novo Proteins from a Designed Combinatorial Library | Teaching in Philadelphia, PA. |
| Atrish Bagchi | Chemistry | AB 2010 | Synthetic Biology: Metal-Binding Proteins from a Combinatorially Designed Artificial Proteome | Grad Student at UPenn |
| Kara McKinley | Molecular Biology | AB 2010 | Conditionally Essential and Promiscuous Function of De Novo Designed Proteins in Escherichia coli | Grad Student at MIT (Biology) |
| David Canner | Chemistry | AB 2011 | Examination of Efficacy of Pro-Aggregation Compounds in the Treatment of A-Beta Mediated Toxicity in a Drosophila melanogaster Alzheimer’s Disease Model | Grad Student at MIT (Biology) |
| Dan Echelman | Chemistry | AB 2011 | A biochemical characterization of a synthetic iron metabolism protein | Columbia University, MD/PhD program |
| Ros Kellen | Molecular Biology | AB 2011 | De novo four-helix bundles restore cell growth of auxotrophic Escherichia coli | Cornell University Medical School |
| Charlotte Rajasingh | Chemistry | AB 2011 | Characterization of De Novo Sequences that Rescue the Deletion of Phosphoserine Phosphatase in Escherichia coli | Stanford University Medical School |
| Maria Aristova | Chemical Engineering | AB 2012 | Characterizing the Function of a de novo Protein Conferring Antibiotic Resistance in E. Coli | Northwestern, MD/PhD program |
| Laura Bock | Molecular Biology | AB 2012 | Characterization of a de novo Sequence that Rescues the Delection of Phosphoadenosine Phosphosulfate Reductase in E. Coli | Consultant at Oliver Wyman |
| Richard Hildreth | Molecular Biology | AB 2013 | Investigations into the Activity of the Novel Protein SynFes-2 | |
| Eliza Hompe | Chemistry | AB 2014 | Investigation into the Enzymatic Function of an Evolved de novo Protein | |
| Jack Greisman | Molecular Biology | AB 2014 | Characterization of Functional Proteins from a Combinatorial Library of de novo Designed Sequences | D.E. Shaw Research |
| Kelly Ivins-O’Keefe | Chemistry | AB 2014 | Probing Unevolved Sequence Space for Metal Binding | Uniformed Services University Medical School |
| James Agolia | Chemistry | AB 2016 | Toward Functional de novo Proteins: Searching for Kemp Elimination Catalysis and Embelin Binding in Designed Combinatorial Libraries | |
| Bennett McIntosh | Chemistry | AB 2016 | Negative Selection with a de novo Library of Amphiphilic Peptides from Unevolved Sequence space | Scientific Writer for the Hertz Foundation |
| Matthew Volpe | Chemical & Biological Engineering | BSE 2016 | Structural Characterization of a Computationally Designed de novo Protein Library by NMR | Grad Student at Harvard (Chemistry and Chemical Biology) |
| Taylor Myers | Chemistry | AB 2017 | Characterization of Functionally Active Proteins from a Combinatorial Library of Novel Sequences | |
| Elizabeth Stanley | Chemical & Biological Engineering | BSE 2018 | Enhancing Expression of Hydrophobic Peptides in E. coli via Fusion to Novel Proteins | Brigham and Women’s Hospital at Harvard University Medical School |
| Emily Schneider | Chemical & Biological Engineering | BSE 2018 | Creating a Library of Functional, Well Ordered de novo Proteins | Broad Institute at Harvard University and MIT |