Alumni

Recent Alumni

Post-Docs

Name Year(s) Project Where Are They Now?
Christine Wurth 2000 – 2002 Mapping the Sequence Determinants of the Aggregation of the Alzheimer’s A-beta Peptide Hoffmann-La Roche Ltd, Basel, Switzerland
Luke Bradley 2001 – 2006 Design and Construction of Combinatorial Libraries of Novel Proteins Assistant Professor, University of Kentucky Medical School, Lexington, KY.
Michael Ackerman 2003 – 2005 Structural Studies of de Novo Designed Beta Sheet Proteins Bristol-Myers Squibb, Princeton NJ.
Ryoichi Arai 2006 – 2007 Phage Display of Combinatorial Libraries of Novel Proteins Assistant Professor, Shinshu University, Nagano, Japan.
Izhack Cherny 2007 – 2011 Functional Proteins from an Artificial Proteome Felsenstein Medical Research Center
Betsy Smith 2010 – 2014 Laboratory evolution of de novo proteins toward higher activity and enhanced specificity Assistant Professor, Elimra College

Graduate Students

Name Department Year(s) Thesis Title Where Are They Now?
Dave Moffet Chemistry Ph.D. 2002 Functional Proteins From a Designed Combinatorial Library Associate Professor, Loyola Marymount University, Los Angeles, CA.
Yinan Wei Chemistry Ph.D. 2003 Structural and Functional Studies of Well Folded Alpha Helical Proteins from a Designed Combinatorial Library Associate Professor, University of Kentucky, Lexington, KY.
Aditi Das Chemistry Ph.D. 2005 Electrochemical and Functional Studies of de Novo Alpha Helical Proteins from a Designed Combinatorial Library Assistant Professor, University of Illinois-Urbana Champaign
Woojin Kim Chemistry Ph.D. 2006 Sequence Determinants and Inhibition of the Aggregation of the Alzheimer’s ABeta Peptide Harvard Medical School
Abi Go Chemistry Ph.D. 2008 Structural and Dynamics of de Novo Proteins form a Designed Superfamily of 4-Helix Bundles Univeristy of Houston Law School
Shona Patel Chemical Engineering Ph.D. 2008 The Functional Potential of De Novo Designed Four-Helix Bundle Proteins Merck Inc, West Point, PA.
Jermont Chen Chemistry Ph.D. 2008 Using High Throughput Screens to Identify Lead Compounds for Alzheimer’s Disease Theraputics Propulsion Directorate, Wright-Patterson Air Force Base, OH.
Mike Fisher Molecular Biology Ph.D. 2009 Toward de Novo Genomes Informed by Protein Design University of California – Berkley.
Emily Breneman Chemistry M.A. Screening de Novo Four-Helix Bundle Protein Libraries for Enzymatic Activity Using mRNA Display Vector Biolabs, Inc., Recording for the Blind & Dyslexic
Angela Fortner-McKoy Chemistry Ph.D 2011 Characterization of Novel Inhibitors of Alzheimer’s Peptide Aggregation and Implications for Disease Therapeutics Lecturer, Wheaton College
Maria Korolev Chemistry Ph.D 2013 Investigating the mechanism of two synthetic proteins found to rescue E. coli auxotrophic strains ΔgltA and Δges Lecturer at University of Florida

Undergraduate Students

Name Department Year(s) Thesis Title Where Are They Now?
Anna Wang Chemistry AB 2006 Sequence, Expression, and Structural Characterization of a High-Quality De Novo Combinatorial Four Helix Bundle Library Harvard University, Cambridge MA
Jesse Platt Chemistry AB 2007 Biophysical Characterization of De Novo Four Helix Bundle Proteins University of Pennsylvania Medical School, Philidelphia PA.
Ellen Duncan Chemistry AB 2007 Expression and Enzymatic Activity in Proteins from a Combinatorial Library of De Novo Proteins Columbia University Medical School
Debbie Chen Molecular Biology AB 2007 The Aβ42-GFP Fusion Screen: A High Throughput Screen for Compounds that Inhibit Aggregation of the Alzheimer’s Peptide University of Connecticut Medical School
Sayuri Jinadasa Chemistry AB 2008 Screening, Purification, and Kinetic Characterization of de novo Proteins from a Designed Combinatorial Library Columbia University Medical School, New York, NY.
Anne Armstrong Chemistry AB 2008 Exploring the Primary Sequence Det, erminants of Amyloid Beta Aggregation: Towards a Targeted Therapeutic Approach to Alzheimer’s Disease Mount Sinai Medical School
Sara Viola Molecular Biology AB 2008 Novel Proteins from a Designed Combinatorial Library Restore Prototrophy in Single Gene knockouts of Escherichia Coli. Columbia University Medical School, New York, NY
Steve Sasson Chemistry AB 2009 A Bacterial Surface Display Library for the High-Throughput Screening and Selection of De Novo Designed Four-Helix Bundle Proteins JP Morgan, New York, NY
Sam Leachman Chemistry AB 2009 Redesigning a Dynamic Artificial Protein University of California, Berkeley
Beverly Hon Molecular Biology AB 2009 Novel Proteins from a Designed Combinatorial Library Suppress Conditional Auxotrophs in Saccharomyces Cerevisiae University of Medicine and Dentistry of New Jersey
Jessica Langholtz Chemistry AB 2009 Screening and Enzymatic Characterization of De Novo Proteins from a Designed Combinatorial Library Teaching in Philadelphia, PA.
Atrish Bagchi Chemistry AB 2010 Synthetic Biology: Metal-Binding Proteins from a Combinatorially Designed Artificial Proteome Grad Student at UPenn
Kara McKinley Molecular Biology AB 2010 Conditionally Essential and Promiscuous Function of De Novo Designed Proteins in Escherichia coli Grad Student at MIT (Biology)
David Canner Chemistry AB 2011 Examination of Efficacy of Pro-Aggregation Compounds in the Treatment of A-Beta Mediated Toxicity in a Drosophila melanogaster Alzheimer’s Disease Model Grad Student at MIT (Biology)
Dan Echelman Chemistry AB 2011 A biochemical characterization of a synthetic iron metabolism protein Columbia University, MD/PhD program
Ros Kellen Molecular Biology AB 2011 De novo four-helix bundles restore cell growth of auxotrophic Escherichia coli Cornell University Medical School
Charlotte Rajasingh Chemistry AB 2011 Characterization of De Novo Sequences that Rescue the Deletion of Phosphoserine Phosphatase in Escherichia coli Stanford University Medical School
Maria Aristova Chemical Engineering AB 2012 Characterizing the Function of a de novo Protein Conferring Antibiotic Resistance in E. Coli Northwestern, MD/PhD program
Laura Bock Molecular Biology AB 2012 Characterization of a de novo Sequence that Rescues the Delection of Phosphoadenosine Phosphosulfate Reductase in E. Coli Consultant at Oliver Wyman
Richard Hildreth Molecular Biology AB 2013 Investigations into the Activity of the Novel Protein SynFes-2
Eliza Hompe Chemistry AB 2014 Investigation into the Enzymatic Function of an Evolved de novo Protein
Jack Greisman Molecular Biology AB 2014 Characterization of Functional Proteins from a Combinatorial Library of de novo Designed Sequences D.E. Shaw Research
Kelly Ivins-O’Keefe Chemistry AB 2014 Probing Unevolved Sequence Space for Metal Binding Uniformed Services University Medical School